Sunday, March 29, 2020
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Mouse allergen in schools makes asthma worse

Do air-borne allergens in schools affect students’ asthma symptoms? A new article by Wanda Phipatanakul, MD, MS, of Boston’s Children’s Hospital and Harvard Medical School, Boston, and coauthors examined that question in a study that included 284 students, ages 4 to 13, enrolled at 37 inner-city schools in the northeastern United States.

The article is published by the American Medical Association in the journal JAMA Pediatrics.

Classroom and home dust samples linked to the students were collected and analyzed for common indoor allergens, including rat, mouse, cockroach, cat, dog, and dust mites. Associations between school exposure to allergens and asthma outcomes were adjusted for exposure to the allergens at home.

Mouse allergen was the most commonly detected allergen in schools and homes. Higher exposure to mouse allergen at school was associated with increased asthma symptoms and lower lung function, according to the results.

None of the other airborne allergens were associated with worse asthma outcomes. While cat and dog allergens were commonly detected in the schools, dust mite levels were low and cockroach and rat allergens were mostly undetectable in schools and homes.

Limitations of the study include results that may not be generalizable to other cities where other allergens may be predominant in schools.

“These findings suggest that exposure reduction strategies in the school setting may effectively and efficiently benefit all children with asthma. Future school-based environmental intervention studies may be warranted,” the authors conclude.

Paul Katula is the executive editor of the Voxitatis Research Foundation, which publishes this blog. For more information, see the About page.

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